Penn State
Profile

Xiang Zhu

Assistant Professor

Statistics

Email xkz5224@psu.edu
Scopus H-index 14
Scopus Citations 1113

Pure Profile

ORCID iD

Education

  • PhD, Statistics - University of Chicago - 2017
  • BS, Statistics - Nankai University - 2012

Publications

Genetic effects of sequence-conserved enhancer-like elements on human complex traits, Genome Biology, 2024

Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis, Genome Biology, 2022

Nested epistasis enhancer networks for robust genome regulation, Science, 2022

A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids, American Journal of Human Genetics, 2022

Large-scale genome-wide association study of coronary artery disease in genetically diverse populations, Nature Medicine, 2022

Leveraging cell-type-specific regulatory networks to interpret genetic variants in abdominal aortic aneurysm, Proceedings of the National Academy of Sciences of the United States of America, 2022

A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation, Nature Genetics, 2022

The power of genetic diversity in genome-wide association studies of lipids, Nature, 2021

Modeling regulatory network topology improves genome-wide analyses of complex human traits, Nature Communications, 2021

The genetic architecture of DNA replication timing in human pluripotent stem cells, Nature Communications, 2021

A genome-wide association study of chronic ALT-based NAFLD in the Million Veteran Program with histological and radiological validation, Hepatology, 2021

Associations of Genetically Predicted Lp(a) (Lipoprotein [a]) Levels With Cardiovascular Traits in Individuals of European and African Ancestry, Circulation: Cardiovascular Genetics, 2021

Chromatin accessibility landscape and regulatory network of high-altitude hypoxia adaptation, Nature Communications, 2020

LPA variants are associated with aortic valve stenosis, heart failure and chronic kidney disease, Circulation, 2020

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis, Nature Genetics, 2020

Performance of polygenic risk scores for coronary artery disease in the Million Veteran Program, Circulation, 2019

Large-scale genome-wide enrichment analyses identify new trait-associated genes and pathways across 31 human phenotypes, Nature Communications, 2018

Bayesian large-scale multiple regression with summary statistics from genome-wide association studies, Annals of Applied Statistics, 2017

Opposing effects of nitrogen and water addition on soil bacterial and fungal communities in the Inner Mongolia steppe: A field experiment, Applied Soil Ecology, 2016

Effects of conventional and reduced N inputs on nematode communities and plant yield under intensive vegetable production, Applied Soil Ecology, 2013

The Response of Soil Nematode Community to Nitrogen, Water, and Grazing History in the Inner Mongolian Steppe, China, Ecosystems, 2012